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Apppreciate peoples genuine thoughts on this please
#41
My first instinct is that 1000mg 5-HTP is WAYY too much.

Secondly, 5-HTP really needs to be a post-roll supplement as there are risks associated with taking it alongside MDMA.

The antioxidants need to be taken before the MDMA.

(20-11-2014, 06:07 PM)TKK Wrote: 5-HTP, like Prozac, needs to taken regularly over approximately three weeks to gain any potential benefit.
For normal indications what you have said is true but for attenuating MDMA neurotoxicity it is not - immediately after MDMA use is optimal, though prozac and 5-HTP have very different mechanisms for their protective effects in these cases. Attenuation of 3,4-methylenedioxymethamphetamine (MDMA) induced neurotoxicity with the serotonin precursors tryptophan and 5-hydroxytryptophan


(20-11-2014, 06:32 PM)Kingbuyer Wrote: The reason i don't believe the antioxidant will work is because i remember reading a study like this one where asorbic acid was given to rats the amount necessary to protect from MDMA nerotoxity would destroy you stomach. Link
Vitamin C is a good antioxidant but its high water solubility makes it less suitable for entering the brain to deal with MDMA neurotoxicity. ALA is better for this reason but it still has a short half life.

There are some great literature reviews on reddit on this topic, well worth a read:
https://www.reddit.com/r/Borax/comments/...otoxicity/
https://www.reddit.com/r/DrugNerds/comme...tabolites/
https://www.reddit.com/r/DrugNerds/comme...ementation

The "RaveAid" product has already cornered the market for this type of product in north america.
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RE: Apppreciate peoples genuine thoughts on this please - by Allan - 15-09-2015, 03:56 PM



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